Location: SLC transporters @ 378f5bf13111 / Facilitated transporter / CellMLV2 / GLUT1_BG.sedml

Author:

Weiwei Ai <wai484@aucklanduni.ac.nz>

Date:

2024-04-24 10:15:46+12:00

Desc:

Correct the direction of ss flux; update the fast parameters (so the solver can handle)

Permanent Source URI:

http://models.cellml.org/workspace/b65/rawfile/378f5bf1311102d61933906b9747d332a3ea69cf/Facilitated transporter/CellMLV2/GLUT1_BG.sedml

<?xml version="1.0" encoding="UTF-8"?>
<sedML xmlns="http://sed-ml.org/sed-ml/level1/version4" level="1" version="4">
  <listOfModels>
    <model id="GLUT1_BG_24_io" language="urn:sedml:language:cellml" source="GLUT1_BG.cellml">
      <listOfChanges>
        <changeAttribute target="/cellml:model/cellml:component[@name=&quot;params_BG&quot;]/cellml:variable[@name=&quot;g_i&quot;]/@initial_value" newValue="24"/>
        <changeAttribute target="/cellml:model/cellml:component[@name=&quot;params_BG&quot;]/cellml:variable[@name=&quot;g_o&quot;]/@initial_value" newValue="1e-4"/>
      </listOfChanges>
    </model>
  </listOfModels>
  <listOfSimulations>
    <uniformTimeCourse id="sim_GLUT1_BG_24_io" initialTime="0" outputStartTime="25" outputEndTime="25" numberOfSteps="0">
      <algorithm name="LSODA" kisaoID="KISAO:0000088">
        <listOfAlgorithmParameters>
          <algorithmParameter name="max_step" kisaoID="KISAO:0000467" value="100"/>
        </listOfAlgorithmParameters>
      </algorithm>
    </uniformTimeCourse>
  </listOfSimulations>
  <listOfTasks>
    <task id="task_GLUT1_BG_24_io" modelReference="GLUT1_BG_24_io" simulationReference="sim_GLUT1_BG_24_io"/>
  </listOfTasks>
  <listOfDataGenerators>
    <dataGenerator id="dg_GLUT1_BG_24_io_t" name="dg_GLUT1_BG_24_io_t">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> GLUT1_BG_24_io_t </ci>
          <ci> scale </ci>
        </apply>
      </math>
      <listOfVariables>
        <variable id="GLUT1_BG_24_io_t" target="/cellml:model/cellml:component[@name=&quot;GLUT1_BG&quot;]/cellml:variable[@name=&quot;t&quot;]" taskReference="task_GLUT1_BG_24_io" modelReference="GLUT1_BG_24_io"/>
      </listOfVariables>
      <listOfParameters>
        <parameter id="scale" value="1"/>
      </listOfParameters>
    </dataGenerator>
    <dataGenerator id="dg_GLUT1_BG_24_io_v_r1" name="dg_GLUT1_BG_24_io_v_r1">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> GLUT1_BG_24_io_v_r1 </ci>
          <ci> scale </ci>
        </apply>
      </math>
      <listOfVariables>
        <variable id="GLUT1_BG_24_io_v_r1" target="/cellml:model/cellml:component[@name=&quot;GLUT1_BG&quot;]/cellml:variable[@name=&quot;v_r1&quot;]" taskReference="task_GLUT1_BG_24_io" modelReference="GLUT1_BG_24_io"/>
      </listOfVariables>
      <listOfParameters>
        <parameter id="scale" value="-1"/>
      </listOfParameters>
    </dataGenerator>
    <dataGenerator id="dg_GLUT1_BG_24_io_q_init_Ai" name="dg_GLUT1_BG_24_io_q_init_Ai">
      <math xmlns="http://www.w3.org/1998/Math/MathML">
        <apply>
          <times/>
          <ci> GLUT1_BG_24_io_q_init_Ai </ci>
          <ci> scale </ci>
        </apply>
      </math>
      <listOfVariables>
        <variable id="GLUT1_BG_24_io_q_init_Ai" target="/cellml:model/cellml:component[@name=&quot;GLUT1_BG&quot;]/cellml:variable[@name=&quot;q_init_Ai&quot;]" taskReference="task_GLUT1_BG_24_io" modelReference="GLUT1_BG_24_io"/>
      </listOfVariables>
      <listOfParameters>
        <parameter id="scale" value="11.1111111111111"/>
      </listOfParameters>
    </dataGenerator>
  </listOfDataGenerators>
  <listOfOutputs>
    <report id="report_task_GLUT1_BG_24_io" name="report_task_GLUT1_BG_24_io">
      <listOfDataSets>
        <dataSet id="dataset_GLUT1_BG_24_io_t" label="t" dataReference="dg_GLUT1_BG_24_io_t"/>
        <dataSet id="dataset_GLUT1_BG_24_io_v_r1" label="v_r1" dataReference="dg_GLUT1_BG_24_io_v_r1"/>
        <dataSet id="dataset_GLUT1_BG_24_io_q_init_Ai" label="q_init_Ai" dataReference="dg_GLUT1_BG_24_io_q_init_Ai"/>
      </listOfDataSets>
    </report>
  </listOfOutputs>
</sedML>